Product Description
Ref-SKU:
006N-01922 Recombinant HIV-1 plasmid (derived from pNL4-3) with the indicated mutations in the protease gene, which have been reported in the context of clinical drug resistance to HIV protease inhibitors.
Product Risk Group:
Information on the related virus
ICTV Taxonomy:
Virus name:
Subspecies:
Group M virus
Strain:
clade B
Isolate:
The recombinant clone NL4-3 was derived from proviral DNA isolated from human HIV-1 positive cells
Genotype:
Group M, clade B
Cloned Product: Yes
Special feature:
Can it be used to produce GMO:
No
Biosafety restrictions:
Plasmid DNA itself is not infectious unless transfected into suitable cells. Will produce live HIV-1 after transfection into mammalian cells. Infectivity of resulting virus has been verified! The virus has proven drug resistance against clinical HIV protease inhibitors
Region encompassed in this Product:
entire genome of HIV-1
Plasmid:
Plasmid selection:
TAG:
Sequencing:
Fully sequenced
Sequence controlled:
Yes
Mutations:
No mutation compared to the reference sequence
Nucleic Acid preparation technique:
Plasmid-Miniprep (Macherey Nagel)
Storage conditions:
TE Buffer -20C
Shipping conditions:
IATA Classification: