Product Description
Ref-SKU:
006N-01988 Plasmid contains the entire genome of HIV-1 (NL4-3) with specific mutations in the protease gene, which can confer drug resistance to specific HIV-1 protease inhibitors. The respective mutations have been reported in viruses from HIV-infected individuals on protease inhibitors with virologic therapy failure.
Product Risk Group:
Information on the related virus
ICTV Taxonomy:
Virus name:
Subspecies:
Strain:
Isolate:
Cloned Product: Yes
Can it be used to produce GMO:
No
Biosafety restrictions:
Plasmid contains the entire genome of HIV-1 (NL4-3) with specific mutations in the protease gene, which can confer drug resistance to specific protease inhibitors.
Might produce infectious virus after transfection into suitable human cells.
Region encompassed in this Product:
entire HIV-1 genome
Plasmid:
Plasmid selection:
TAG:
Sequencing:
Fully sequenced
Sequence checked:
Yes
Mutations:
No mutation compared to the reference sequence
Nucleic Acid preparation technique:
ion exchange column (Macherey Nagel)
Storage conditions:
TE Buffer -20C
Shipping conditions:
IATA Classification:
Virus host type:
Information about the origin of the product
Recombinant product:
This product is a recombinant product
Biological material origin:
Synthetic origin & Natural origin
Natural part identification: NL4-3
Natural part identification:
NL4-3
Genbank reference:
Collection date: BEFORE
Wednesday, 1 September, 2010
Country of collection:
Synthetic part identification: Point mutation in the protease gene, position 45 and 76
Synthetic part identification:
Point mutation in the protease gene, position 45 and 76
Modifications from the reference sequence(s):
The sequence(s) of this synthetic product has been modified from the sequence listing provided as Genbank references