Product Description
Ref-SKU:
006N-01921 Recombinant HIV-1 virus with the indicated mutations in the protease gene. Mutations have been reported from drug resistant viral variants emerging in vivo, e.g. after treatment with the HIV protease inhibitor saquinavir
Product Risk Group:
Information on the related virus
ICTV Taxonomy:
Virus name:
Subspecies:
Group M virus
Strain:
clade B
Isolate:
The recombinant clone NL4-3 was derived from proviral DNA isolated from human HIV positive cells
Genotype:
Group M, clade B
Cloned Product: Yes
Special feature:
Can it be used to produce GMO:
No
Biosafety restrictions:
Plasmid DNA itself is not infectious unless transfected into suitable cells; will produce live HIV-1 after DNA-transfection of human/mammalian cells
Region encompassed in this Product:
entired virus genome
Plasmid:
Plasmid selection:
TAG:
Sequencing:
Fully sequenced
Sequence controlled:
Yes
Mutations:
No mutation compared to the reference sequence
Storage conditions:
TE Buffer -20C
Shipping conditions:
IATA Classification:
Note:
This plasmid has been generated as a drug-resistant variant of HIV. It carries mutations that mediate resistance to several clinical protease inhibitors for HIV, including saquinavir