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022N-03915 Nucleic Acid T7-driven tetracistronic Ebola virus trVLP system expressing a Marburg virus glycoprotein and with a Renilla-luciferase reporter (pT7.1-4cis-EBOV-vRNA-MARV-GP-hrLuc), recombinant non-infectious system Ebola virus Mayinga / Marburg virus Musoke (8 plasmids Reverse genetics-based life cycle modelling system that allows modelling of Ebola virus genome replication and transcription, viral protein synthesis, virus assembly, budding, and Marburg virus entry into target cells under BSL1 conditions. Consists of 1) a plasmid encoding a T7-driven tetracistronic minigenome encoding a Renilla luciferase reporter and the Ebola virus proteins VP40 and VP24, and the Marburg virus protein GP; 2) expression plasmids for the Ebola virus protein NP, VP35, VP30, and L; and 3) expression plasmids for the accessory proteins T7 polymerase (for initial transcription of the minigenome), Tim1 (attachment factor) and firefly luciferase (as control). Access is restricted to non-commercial research institutions only. Further descriptions of the different trVLP systems can be found at https://www.fli.de/en/institutes/institute-of-molecular-virology-and-cell-biology-imvz/laboratories/laboratory-for-molecular-biology-of-filoviruses/ Marburg marburgvirus Marburgvirus Cat3 In stock RG1 FLI 900€ View all details on this product...
022N-03916 Nucleic Acid T7-driven tetracistronic Ebola virus trVLP system expressing a Marburg virus glycoprotein and with a Nano-luciferase reporter (pT7.1-4cis-EBOV-vRNA-MARV-GP-nluc), recombinant non-infectious system Ebola virus Mayinga / Marburg virus Musoke (8 plasmids) Reverse genetics-based life cycle modelling system that allows modelling of Ebola virus genome replication and transcription, viral protein synthesis, virus assembly, budding, and Marburg virus entry into target cells under BSL1 conditions. Consists of 1) a plasmid encoding a T7-driven tetracistronic minigenome encoding a Nano luciferase reporter and the Ebola virus proteins VP40 and VP24, and the Marburg virus protein GP; 2) expression plasmids for the Ebola virus protein NP, VP35, VP30, and L; and 3) expression plasmids for the accessory proteins T7 polymerase (for initial transcription of the minigenome), Tim1 (attachment factor) and firefly luciferase (as control). Access is restricted to non-commercial research institutions only. Further descriptions of the different trVLP systems can be found at https://www.fli.de/en/institutes/institute-of-molecular-virology-and-cell-biology-imvz/laboratories/laboratory-for-molecular-biology-of-filoviruses/ Marburg marburgvirus Marburgvirus Cat3 In stock RG1 FLI 900€ View all details on this product...

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