The AAV8 expresses an anti-CD8 targeting antibody (clone YTS169) allowing long-term depletion of CD8 T cells. The isotope of the depletion antibody is a mouse IgG2a.
Unit: 1 unit equals a 100 µl with a guaranteed titer of >10e11 vg (on average 5x10e11 vg)
The AAV8 expresses an anti-CD20 targeting antibody (clone 18B12) allowing long-term depletion of B cells. The isotope of the depletion antibody is a mouse IgG2a.
Unit: 1 unit equals a 100 µl with a guaranteed titer of >10e11 vg (on average 5x10e11 vg)
The AAV8 expresses the VI10 antibody targeting the glycoprotein of vesicular stomatitis virus. It can be used as a control for depletion-AAVs. The isotope of the antibody is a mouse IgG2a.
Unit: 1 unit equals a 100 µl with a guaranteed titer of >10e11 vg (on average 5x10e11 vg)
The AAV8 expresses an anti-Gr-1 targeting antibody (clone RB6.8C5) allowing the depletion of neutrophils and other myeloid cells. The isotope of the depletion antibody is a mouse IgG2a.
Unit: 1 unit equals a 100 µl with a guaranteed titer of >10e11 vg (on average 5x10e11 vg)
The AAV8 expresses an anti-NK1.1 targeting antibody (clone PK136) allowing the long-term depletion of NK cells. The isotope of the depletion antibody is a mouse IgG2a.
Unit: 1 unit equals a 100 µl with a guaranteed titer of >10e11 vg (on average 5x10e11 vg)
The AAV8 expresses an anti-CD4 targeting antibody (clone YTS191) allowing the long-term depletion of CD4 T cells. The isotope of the depletion antibody is a mouse IgG2a.
Unit: 1 unit equals a 100 µl with a guaranteed titer of >10e11 vg (on average 5x10e11 vg)
LCMV Armstrong expressing the glycoprotein of strain WE and carrying a mutation N63K to convert the GP61-80 CD4 epitope to the sequence of the Armstrong/Clone strain and, additionally, carrying a glycoprotein Y72F mutati
Plasmid for expression of the LCMV S-segment with heterologous arenavirus GP - Junin with glycosylation site restored as described in Sommerstein et al. 2015 PLoS Pathos.
vaccinia virus WR strain. This Vaccinia virus[WR] is preserved under Viral Storage Medium -80C.Tests for the presence of mycoplasmae were not performed. To confirm its identity the virus has been fully sequenced.
