Plasmid contains the entire genome of HIV-1 (NL4-3) with the respective specific mutations in the protease gene. These may confer drug resistance to specific HIV protease inhibitors and have been identified in clinical specimens from individuals with therapeutic failure.
Plasmid containing an NL4-3 based HIV-1 genome with a big deletion between SalI site (5785) and XhoI site (8887), leading to a deletion of the viral genes vpu,env, tat, rev. Also the "rev-response-element" RRE is missing, leading to a lack of expression also of the gag-pol genes
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