EVA

Expression Plasmid of AIBV Macro Domain, in fusion with a N-Terminal His tag coding

Expression Plasmid of AIBV Macro Domain+UNK+ZrPLpro2 Domains, in fusion with a N-Terminal His tag coding sequence for expression in E. coli ADRP+UNK+ZrPLpro2 Domain (UNK)

Expression Plasmid of AIBV Nsp16, Full gene (2'O MTase), in fusion with a C-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of AIBV Nsp16, Full gene (2'O MTAse), in fusion with a N-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of AIBV Nsp15, Full gene (NendoU), in fusion with a C-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of EqTV Nsp15+16, Full genes (Endonuclease+Methyltransferase), in fusion with a N-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of EqTV Nsp15+16, Full genes (Endonuclease+Methyltransferase), in fusion with a C-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of EqTV Nsp15, Full gene (UNK), in fusion with a N-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of EqTV Nsp 15, Full gene (UNK), in fusion with a C-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of EqTV Nsp15, Full gene (NendoU), in fusion with a C-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of EqTV Nsp13, Full gene (helicase), in fusion with a C-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of CoV229E Macro Domain, in fusion with a N-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of TGEV Nsp4, Full gene (UNK), in fusion with a N-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of TGEV Nsp9, Full gene (RNA binding protein), in fusion with a N-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of TGEV Nsp9, Full gene (RNA binding protein), in fusion with a C-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of TGEV Nsp8, Full gene (UNK), in fusion with a N-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of TGEV Nsp8, Full gene (UNK), in fusion with a C-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of TGEV Nsp7, Full gene (UNK), in fusion with a N-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of TGEV Nsp7, Full gene (UNK), in fusion with a C-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of TGEV Nsp5, Full gene (Protease), in fusion with a N-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of TGEV Nsp5, Full gene (protease), in fusion with a C-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of TGEV Nsp13, Full gene (Helicase), in fusion with a C-Terminal His tag coding sequence for expression in E. coli

Expression Plasmid of TGEV Nsp10, Full gene (UNK), in fusion with a N-Terminal His tag coding sequence for expression in E. coli

Through direct cloning and expression of the variable heavy chains (VHHs) of HCAbs from the bone marrow of MERS-CoV infected dromedaries, MERS-CoV specific VHHs or nanobodies were produced. VHH-83 binds with exceptionally high affinity to the receptor binding domain of the viral spike protein. In vitro, this VHH efficiently blocks virus entry at picomolar concentrations

Serum obtained from dromedary camels immunized with a MVA vaccine expressing the spike protein and challenged with MERS-CoV.