Plasmid contains the entire genome of HIV-1 with a specific mutation in the protease gene, which has been described as a polymorphic mutation. It is unclear, whether it can confer drug resistance to specific HIV-1 PR inhibitors directly. It has been shown in cell culture that the presence of the 63P change leads to higher "replicative fitness" of the virus. The respective mutations have been reported in viruses from HIV-infected individuals on PR inhibitors with virologic therapy failure.
Feline Parvovirus, Panleukopenia Virus isolate 17DIAPD53928/3 isolated from intestine of a cat, collected in 2017 in Italy (FriuliVeneziaGiulia region)
Canine Parvovirus type 2 isolate 17DIAPD55092-2 (type: new 2a) isolated from intestine of a dog, collected in 2017 in Italy (Friuli Venezia Giulia region)
Canine Parvovirus type 2 isolate 17DIAPD57033-8 (type: intervet vaccinal strain) isolated from intestine of a dog, collected in 2017 in Italy (Veneto region)