MERS-CoV single chain antibody HCAb-83


EVAg

Produced by
: ERASMUS-MC
Shipping From
: Rotterdam - NL

Product Description

Ref-SKU:
011A-02999
HCAb-83 is a MERS-CoV specific camel/human chimeric heavy chain only antibody (HCAb) - composed of the camel VHH-83 linked to a human Fc domain lacking the CH1 exon Through direct cloning and expression of the variable heavy chains (VHHs) of HCAbs from the bone marrow of MERS-CoV infected dromedaries, MERS-CoV specific VHHs or nanobodies were produced. VHH-83 binds with exceptionally high affinity to the receptor binding domain of the viral spike protein. In vitro, HCAb-83 efficiently blocks virus entry at picomolar concentrations
Product Risk Group: 

Information on the related virus

Virus name: 


Unit definition: 
50 µg

In stock

500,00 €
(Cost per access for Academics)

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Product type: 
Antibody
Targeted antigen: 
Protein
Antibody type: 
Monoclonal
Antibody purified by affinity: 
Yes
Production system: 
Antibody purified by affinity: Yes, contains His tag
Antibody characterization method(s): 
ELISA
IFA
Neutralisation
Immunoprecipitation
Biophysical method
Specificity documented: 
Yes
Shipping conditions: 
IATA Classification: